LAG3 Protein (C-His, Cynomolgus)

Product Specifications

Abbreviation

LAG3

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

1.Immobilized LAG3 Protein, Cynomolgus, Recombinant (74 Pro, His Tag) (Cat:90841-C08H) at 2 μg/mL (100 μL/well) can bind FGL1 Protein, Cynomolgus, Recombinant (hFc Tag) (Cat:90926-C02H), the EC50 is 140-760 ng/mL. 2.Immobilized Recombinant Cynomolgus LAG3/CD223 (74 Pro, His Tag) Cat: 90841-C08H) at 2μg/mL (100μL/well) can bind Anti-LAG3 (BMS) -IgG4 Antibody, the EC50 is 60-180 ng/mL.

Function

Met1-Leu450, 74 Pro

Molecular Weight

The recombinant LAG3 consists of 437 amino acids and predicts a molecular mass of 47.4 kDa. As a result of glycosylation, it migrates as an approximately 57.73 and 132.72 kDa band in SDS-PAGE under reducing conditions.