JAM2 Protein (C-human IgG1-Fc, Mouse)
Product Specifications
Abbreviation
JAM2
Synonyms
1110002N23Rik,2410030G21Rik,2410167M24Rik, JAM-2, JAM-B, Jam2, Jcam2, VE-JAM, Vejam
Host
HEK 293
Tag
C-human IgG1-Fc
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 70 % as determined by SDS-PAGE
Bioactivity
Measured by the ability of the immobilized protein to support the adhesion of Jurkat human leukemic T cells . When 8 x 10E4 cells/well are added to JAM2-coated plates (0.2 μg/ml and 100 μl/well), approximately 40-55% will adhere specifically after 60 minutes at 37°C.
Function
Met1-Asn236
Molecular Weight
The secreted recombinant mouse JAM-2/Fc is a disulfide-linked homodimeric protein. The reduced monomer comprises 449 amino acids and has a predicted molecular mass of 50.3 kDa. rm JAM-2/Fc monomer migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.
Species
Mouse
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