JAG1 Protein (C-human IgG1-Fc, Human)
Product Specifications
Abbreviation
JAG1
Synonyms
AGS, AGS1, AHD, AWS, CD339, CMT2HH, DCHE, HJ1, JAGL1
Host
HEK 293
Tag
C-human IgG1-Fc
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 85 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Bioactivity
Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 5-30 μg/mL.
Function
Met1-Ser1046
Molecular Weight
The recombinant human JAG1/Fc is a disulfide-linked homodimer. The reduced monomer consists of 1254 amino acids and has a predicted molecular mass of 137 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of human JAG1/Fc monomer is approximately 185.5 kDa due to glycosylation.
Species
Human
Frequently Asked Questions
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