JAG1 Protein (C-His, Human)

Product Specifications

Abbreviation

JAG1

Synonyms

AGS, AGS1, AHD, AWS, CD339, CMT2HH, DCHE, HJ1, JAGL1

Host

HEK 293

Tag

C-His

Endotoxin

< 10 EU per mg protein.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 1.5-15 μg/mL.

Function

Met1-Ser1046

Molecular Weight

The recombinant human JAG1 consists of 1024 amino acids and has a predicted molecular mass of 112 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh JAG1 is approximately 160 kDa due to glycosylation.