ITGA2B & ITGB3 Protein (C-His-AVI, Human)

Product Specifications

Abbreviation

ITGA2B & ITGB3

Host

HEK 293

Tag

C-His-AVI

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

Immobilized Anti-GPIIb/IIIa (Research Grade Abciximab Biosimilar) at 2 μg/mL (100 μL/well) can bind Recombinant Human Integrin alpha 2b beta 3 Protein (I874S, Flag & His & AVI Tag) (Cat: CT131-H49H-B), the EC50 is 8-25 ng/mL (QC tested) .

Function

Met1-Arg993 & Met1-Asp718

Molecular Weight

The recombinant Human Integrin alpha 2b beta 3 Heterodimer comprises 1766 (1030+736) amino acids and has a calculated molecular mass of 193.62 (112.52+81.1) kDa. The apparent molecular mass of Human Integrin alpha 2b beta 3 Heterodimer is approximately 133.9 kDa, 117 kDa and 98 kDa respectively in SDS-PAGE.