INHBA Protein (Native, Human, Mouse, Rat, Cynomolgus, Rhesus, Rabbit)

1.Measured by its ability to inhibit proliferation of MPC-11 cells. The ED50 for this effect is 0.5-5ng/mL. 2.Loaded Recombinant Rabbit ACVR2B Protein, His Tag (Cat. No. 65178-T08H) on HIS1K Biosensor, can bind Recombinant Human / Mouse / Rat / Cynomolgus / Rhesus/ Rabbit Activin A Protein (Cat. No. 10429-HNAH) with an affinity constant of 0.182 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 3.Loaded Recombinant Rabbit ACVR2A Protein, His Tag (Cat. No. 65177-T08H) on HIS1K Biosensor, can bind Recombinant Human / Mouse / Rat / Cynomolgus / Rhesus/ Rabbit Activin A Protein (Cat. No. 10429-HNAH) with an affinity constant of 0.190 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 4.Recombinant Rabbit ACVR2B Protein, His Tag (Cat. No. 65178-T08H) captured on NTA chip, can bind Recombinant Human, Mouse, Rat, Cynomolgus, Rhesus Activin A Protein (Cat. No. 10429-HNAH) with an affinity constant of 6.770 pM as determined in an SPR assay (Biacore 8K) (Routinely tested) .

The recombinant Human / Mouse / Rat / Cynomolgus / Rhesus/ Rabbit INHBA consists of 116 amino acids and predicts a molecular mass of 13 kDa. It migrates as an approximately 15 kDa band in SDS-PAGE under reducing conditions.