IL4R Protein (C-human IgG1-Fc, Cynomolgus)
Product Specifications
Abbreviation
IL4R
Host
HEK 293
Tag
C-human IgG1-Fc
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
Bioactivity
1. Measured by its ability to inhibit IL-4 dependent proliferation of TF-1 human erthroleukemic cells. The ED50 for this effect is 4-16 ng/ml in the presence of 0.2 ng/mL IL-4. 2. Immobilized Recombinant Human IL4 / Interleukin-4 Protein (Cat:11846-HNAE) at 2μg/mL (100μL/well) can bind Recombinant Cynomolgus IL4R Protein (ECD, Fc Tag) (Cat:90897-C02H), the EC50 is 18-56 ng/mL.
Function
Met1-Arg232
Molecular Weight
The recombinant cynomolgus IL4R consists of 445 amino acids and predicts a molecular mass of 50.48 kDa.
Species
Cynomolgus
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