IL27Ra Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

IL27Ra

Synonyms

CRL1, IL-27R, IL-27RA, IL27R, IL27RA, TCCR, UNQ296/PRO336, WSX-1, WSX1, zcytor1

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

Measured by its binding ability in a functional ELISA . Immobilized human IL27 at 20 μg/ml (100 μl/well) can bind human IL27Ra with a linear range of 0.064-1.6 μg/ml.

Function

Met1-Arg514

Molecular Weight

The recombinant human IL27Rα/Fc is a disulfide-linked homodimeric protein after removal of the signal peptide. The reduced monomer consists of 722 amino acids and has a predicted molecular mass of 79 kDa. As a result of glycosylation, rh IL27Rα/Fc monomer migrates as an approximately 105-115 kDa band in SDS-PAGE under reducing conditions.