IL22 Protein (Native, Human)

Product Specifications

Abbreviation

IL22

Synonyms

IL-21, IL-22, IL-D110, IL-TIF, ILTIF, MGC79382, MGC79384, TIFa, TIFIL-23, UNQ3099/PRO10096, zcyto18

Host

E. coli

Tag

Native

Endotoxin

< 10 EU per mg protein.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-MALS.

Bioactivity

1.Measured by its ability to induce IL-10 secretion in COLO 205 human colorectal adenocarcinoma cells. The ED50 for this effect is typically 0.3-1.2 ng/mL. 2.Human small intestinal organoids were cultured with IL22 (Cat#13059-HNAE), FGF10 (Cat#10573-HNAE), EGF (Cat#50482-MNCH), NOG (Cat#50688-M02H) . (Routinely tested) . Data provided by D1 Medical Technology.

Function

Ala34-Ile179

Molecular Weight

The recombinant human IL22 consists of 147 amino acids and predicts a molecular mass of 16.9 KDa. It migrates as an approximately 15 KDa band in SDS-PAGE under reducing conditions. The molecular weight of this protein is around 18.4 kDa verified by SEC-MALS.