IL21R Protein (C-His, Human)

Product Specifications

Abbreviation

IL21R

Synonyms

CD360, IMD56, NILR, UNQ3121/PRO10273

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 92 % as determined by SDS-PAGE. >90% as determined by SEC-HPLC.

Bioactivity

1. Measured by its ability to bind human IL-21 in a functional ELISA. 2.Measured by its ability to inhibit IL-21-induced Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is typically 4-25 ng/mL in the presence of 2ng/mL of recombinant human IL-21.

Function

Met1-Pro236

Molecular Weight

The recombinant human IL21R consists of 228 amino acids and predictes a molecular mass of 26.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh IL21R is approximately 42-46 kDa due to glycosylation.