IL1RN Protein (Native, Human)
Product Specifications
Abbreviation
IL1RN
Synonyms
CRMO2, DIRA, ICIL-1RA, IL-1ra, IL-1ra3, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430, MVCD4
Host
E. coli
Tag
Native
Purity
≥ 95 % as determined by SDS-PAGE
Bioactivity
1. Measured by its binding ability in a functional ELISA. Immobilized human IL1RA at 10 μg/ml (100 μl/well) can bind human IL1R2-Fc (Cat:10111-H02H), The EC50 of human IL1R2-Fc (Cat:10111-H02H) is 0.04-0.1 μg/mL. 2. Measured by its binding ability in a functional ELISA. Immobilized human IL1RA at 10 μg/ml (100 μl/well) can bind human IL1R1-Fc (Cat:10126-H02H), The EC50 of human IL1R1-Fc (Cat:10126-H02H) is 0.08-0.2 μg/mL. 3. Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 250pg/mL IL1a. The EC50 for this effect is typically 3-12 ng/mL.
Function
Arg26-Glu177
Molecular Weight
The recombinant human IL1RA consists of 153 amino acids and predicts a molecular mass of 17.3 kDa which is also estimated by SDS-PAGE.
Species
Human
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