IL1R1 Protein (C-human IgG1-Fc, Cynomolgus)

Product Specifications

Abbreviation

IL1R1

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Measured by its binding ability in a functional ELISA. Immobilized human IL1RA (Cat:10123-HNAE) at 10 μg/ml (100 μl/well) can bind Cynomolgus IL1R1-Fc, The EC50 of Cynomolgus IL1R1-Fc is 0.04-0.08 μg/mL.

Function

Met1-Thr332

Molecular Weight

The recombinant cynomolgus IL1R1 is a disulfide-linked homodimer. The reduced monomer comprises 558 amino acids and has a calculated molecular mass of 62.9 KDa.The apparent molecular mass of the protein is approximately 73-93 KDa respectively in SDS-PAGE.