IL1R1 Protein (C-His, Human)

Product Specifications

Abbreviation

IL1R1

Synonyms

CD121A, CRMO3, D2S1473, IL-1R-alpha, IL-1RT1, IL1R, IL1RA, IL1RT1, P80

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 97 % as determined by SDS-PAGE. ≥ 85 % as determined by SEC-HPLC.

Bioactivity

Measured by its ability to inhibit Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 500 pg/mL IL1b. The EC50 for this effect is typically 40-200 ng/mL.

Function

Met1-Thr332

Molecular Weight

The soluble form of recombinant human IL1R1 consists of 326 amino acids after removal of the signal peptide and has a predicted molecular mass of 37.6 kDa. In SDS-PAGE under reducing conditions, it migrates with an apparent molecular mass of 51-57 kDa due to glycosylation.