IL17RB Protein (C-human IgG1-Fc, Human)

1. Measured by its binding ability in a functional ELISA. 2. Immobilized human IL17BR-Fc at 10μg/mL (100μL/well) can bind biotinylated human Fc-IL25 (Cat:10096-H01H) . The EC50 of human Fc-IL25 (Cat:10096-H01H) is 4.5-10.4ng/mL.

The recombinant human IL17BR/Fc is a disulfide-linked homodimer. The reduced monomer comprises 513 amino acids and has a predicted molecular mass of 56.9 kDa. The apparent molecular mass of the protein is approximately 67 kDa in SDS-PAGE under reducing conditions.