IL17RA Protein (C-His, Human)
Product Specifications
Abbreviation
IL17RA
Synonyms
CANDF5, CD217, CDw217, hIL-17R, IL-17RA, IL17R, IMD51
Host
HEK 293
Tag
C-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 97 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Bioactivity
1. Measured by its binding ability in a functional ELISA. Immobilized recombinant human IL17A at 2 μg/ml (100 μl/well) can bind biotinylated human IL17RA with a linear range of 1.28-32 ng/ml. 2. Measured by its ability to inhibit IL-17-induced mIL-6 secretion by NIH‐3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 103ng/mL in the presence of 5 ng/mL recombinant human IL‐17 (Routinely tested) .
Function
Met1-Trp320
Molecular Weight
The recombinant human IL17RA consists of 299 amino acids and has a predicted molecular mass of 35 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh IL17RA is approximately 52-60 kDa due to glycosylation.
Species
Human
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