IL17A Protein (N-His, Human)

Product Specifications

Abbreviation

IL17A

Synonyms

CTLA-8, CTLA8, IL-17, IL-17A, IL17, ILA17

Host

Baculovirus-insect Cells

Tag

N-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to induce IL-6 secretion by NIH‐3T3 mouse embryonic fibroblast cells in the presense of 20 ng/mL TNFα. The ED50 for this effect is 0.5-2.5 ng/mL.

Function

Gly24-Ala155 (T26A)

Molecular Weight

The recombinant human human IL17A consists of 152 amino acids and predicts a molecular mass of 17.2 KDa. It migrates as an approximately 18.6 and 20.3 KDa band in SDS-PAGE under reducing conditions due to different glycosylation.