IL17A & IL17F Protein (N-Strep II & N-His, Mouse)

Product Specifications

Abbreviation

IL17A & IL17F

Host

HEK 293

Tag

N-Strep II & N-His

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

Immobilized Recombinant Mouse IL17A & IL17F Heterodimer Protein (Strep II & His Tag) (Cat: CT168-M8107H) at 2 μg/mL (100 μL/well) can bind Recombinant Mouse IL17RA / IL17R / CD217 Protein (Fc Tag) (Cat: 50328-M02H), the EC50 is 150-450 ng/mL (QC tested) .

Function

Ala26-Ala158 & Arg29-Ala161

Molecular Weight

The recombinant heterodimer of human IL17A & IL17F consists of 298 (148+150) amino acids and has a calculated molecular mass of 33.2 (16.48+16.72) KDa. It migrates as an approximately 25.8 kDa, 22.1 kDa and 18.6 kDa band in SDS-PAGE under reducing conditions. The molecular weight of this protein is around 39.2 kDa verified by SEC-MALS (Routinely tested) .