IL13Ra2 Protein (C-human IgG1-Fc & His, Human)

1.Measured by its binding ability in a functional ELISA. Immobilized human IL13Ra2-Fch (Cat: 10350-H03H) at 2 μg/mL (100 μl/well) can bind biotinylated human IL13 (Cat: 10369-HNAC), The EC50 of bind biotinylated human IL13 (Cat: 10369-HNAC) is 4-20 ng/mL (Routinely tested) . 2.Immobilized Recombinant Human IL13RA2 / IL13R Protein (His & Fc Tag) (Cat: 10350-H03H) at 1 μg/mL (100 μL/well) can bind Anti- IL-13 R alpha 2/IL13RA2 antibody, human IgG1, the EC50 is 4.5-14.0 ng/mL (QC tested) .

The recombinant human IL13Rα2/Fc is a disulfide-linked homodimeric protein after proteolytic removal of the signal peptide. The reduced monomer consists of 563 amino acids and predicts a molecular mass of 65 kDa. As a result of glycosylation, the rh IL13Rα2/Fc monomer migrates as an approximately 90-100 kDa band in SDS-PAGE under reducing conditions.