IL12RB1 Protein (C-human IgG1-Fc, Human)
Product Specifications
Abbreviation
IL12RB1
Synonyms
CD212, IL-12R-BETA1, IL12R, IL12RB, IMD30
Host
HEK 293
Tag
C-human IgG1-Fc
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 90 % as determined by SDS-PAGE.
Bioactivity
1.Immobilized Recombinant Human IL-23 (IL23A & IL12B Heterodimer) Protein (His Tag) (Cat: CT012-H08H) at 2 μg/mL (100 μL/well) can bind Recombinant Human IL12RB1 Protein (ECD, Fc Tag) (Cat: 11674-H02H), the EC50 is 15-45 ng/mL. 2.Recombinant Human IL12RB1 Protein (ECD, Fc Tag) (Cat: 11674-H02H) captured on Protein A chip, can bind Recombinant Human IL-12 (IL12A&IL12B Heterodimer) Protein (His Tag) (Cat: CT050-H08H) with an affinity constant of 4.108 nM as determined in an SPR assay (Biacore T200) (Routinely tested) .
Function
Met1-Glu540
Molecular Weight
The recombinant Human IL12RB1 consisting of 758 amino acids and has a calculated molecular mass of 84.13 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 98.4 kDa protein in SDS-PAGE under reducing conditions.
Species
Human
Curated Selection
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