IGFBP7 Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

IGFBP7

Synonyms

AGM, FSTL2, IBP-7, IGFBP-7, IGFBP-7v, IGFBPRP1, MAC25, PSF, RAMSVPS, TAF

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 85 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

Immobilized Human CD93 (His Tag) (Cat:12589-H08H) at 2 μg/ml (100 μl/well) can bind Human IGFBP7 (hFc Tag) (cat:13100-H02H) . The EC50 is 8-60 ng/ml.

Function

Met1-Leu282

Molecular Weight

The secreted recombinant human IGFBP7/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 497 amino acids and has a predicted molecular mass of 53.5 kDa. The apparent molecular mass of rh IGFBP7/Fc monomer is approximately 65-70 kDa in SDS-PAGE under reducing conditions.