IGFBP6 Protein (C-His, Mouse)
Product Specifications
Abbreviation
IGFBP6
Synonyms
IGFBP-6, Igfbp6
Host
HEK 293
Tag
C-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 92 % as determined by SDS-PAGE
Bioactivity
Measured by its ability to inhibit the biological activity of IGFII on MCF7 human breast adenocarcinoma cells (Karey, K.P. et al. (1988) Cancer Research 48:4083.) . The ED50 for this effect is typically 1-4 μg/ml in the presence of 20 ng/mL mouse IGFII.
Function
Met1-Gly238
Molecular Weight
The recombinant mouse IGFBP6 consists of 224 amino acids and has a predicted molecular mass of 24 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmIGFBP6 is approximately 30 kDa due to glycosylation.
Species
Mouse
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