IGFBP4 Protein (C-His, Mouse)

Product Specifications

Abbreviation

IGFBP4

Synonyms

Deb2, IBP-4, IGFBP-4, Igfbp4

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Measured in a serum free cell proliferation assay using MCF7 human breast adenocarcinoma cells (Karey, K.P. et al. 1988, Cancer Research 48: 4083.) . The ED50 for this effect is typically 0.1-0.6 μg/ml .

Function

Met1-Glu254

Molecular Weight

The secreted recombinant mouse IGFBP4 consists of 244 amino acids and has a calculated molecular mass of 27.2 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 38 kDa protein in SDS-PAGE under reducing conditions.