IGFBP3 Protein (N-His, Cynomolgus)
Product Specifications
Abbreviation
IGFBP3
Host
HEK 293
Tag
N-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Bioactivity
Measured by its ability to inhibit the biological activity of IGFII on MCF7 human breast adenocarcinoma cells. The ED50 for this effect is typically 25-150 ng/mL in the presence of 14 ng/mL human IGFII.
Function
Gly28-Lys291
Molecular Weight
The recombinant heterodimer of cynomolgus IGFBP3 comprises 284 amino acids and has a calculated molecular mass of 31.1 KDa. The apparent molecular mass of the protein is approximately 41-44 KDa respectively in SDS-PAGE.
Species
Cynomolgus
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