IGF1R Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

IGF1R

Synonyms

CD221, IGFIR, IGFR, JTK13, MGC18216

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE.

Bioactivity

Immobilized Recombinant Human IGF1R Protein (ECD, Fc Tag) (Cat:10164-H02H) at 5 μg/mL (100 μL/well) can bind Recombinant Human IGF-II Protein (Fc & AVI Tag), Biotinylated (Cat:13032-H41H-B), the EC50 is 80-240 ng/mL (QC tested) .

Function

Met1-Asn932

Molecular Weight

The recombinant Human IGF1R comprises 1152 amino acids and the calculated molecular masses for α subunit, β subunit and the single chain of the receptor are approximately 80.4 kDa, 49.44 kDa and 130.44 kDa, respectively. As a result of glycosylation, α subunit, β subunit, and the single chain of the receptor have apparent molecular masses of approximately 130.5 kDa, 88.2 kDa and 216.5 kDa, respectively in SDS-PAGE under reducing conditions.