IFNGR1 Protein (C-human IgG1-Fc, Mouse)

Product Specifications

Abbreviation

IFNGR1

Synonyms

CD119, Ifgr, IFN-gammaR, Ifngr, Ifngr1, Nktar

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Measured by its binding ability in a functional ELISA. Immobilized mouse IFNG-His (Cat:50709-M08H) at 10 μg/ml (100 μl/well) can bind mouse IFNGR1-Fc (cat:50705-M02H) . The EC50 of IFNGR1-Fc (cat:50705-M02H) is 58.2-135.9 ng/ml.

Function

Met1-Asp253

Molecular Weight

The recombinant mouse IFNGR1/Fc is a disulfide-linked homodimer. The reduced monomer consists of 472 amino acids and has a predicted molecular mass of 53 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmIFNGR1/Fc monomer is approximately 70-75 kDa due to glycosylation.