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IFNGR1 Protein (C-His, Mouse)

Product Specifications

Abbreviation

IFNGR1

Synonyms

CD119, Ifgr, IFN-gammaR, Ifngr, Ifngr1, Nktar

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 98 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

1. Immobilized Mouse IFNGR1-His (Cat: 50705-M08H) at 2 μg/mL (100 μl/well) can bind mouse IFNG-Fc (Cat: 50709-M02H), The EC50 of mouse IFNG-Fc (Cat: 50709-M02H) is 20-100 ng/mL. 2. Measured by its ability to inhibit mIFNγ mediated protection of L929 cells infected with vesicular stomatitisvirus (VSV) . The ED50 for this effect is 40-200 ng/mL.

Function

Met1-Asp253

Molecular Weight

The recombinant mouse IFNGR1 consists of 242 amino acids and has a predicted molecular mass of 27.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmIFNGR1 is approximately 40-45 kDa due to glycosylation.