IFNB1 Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

IFNB1

Synonyms

IFB, IFF, IFN-beta, IFNB

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Measured in antiviral assays using WISH human amnion cells infected with vesicular stomatitis virus (VSV) . The ED50 for this effect is 0.08-0.8 ng/mL.

Function

Met1-Asn187

Molecular Weight

The recombinant human IFNβ/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 404 amino acids and has a predicted molecular mass of 46.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh IFNβ/Fc monomer is approximately 52 kDa due to glycosylation.