IFNB1 Protein (C-human IgG1-Fc, Mouse)

Product Specifications

Abbreviation

IFNB1

Synonyms

If1da1, Ifb, IFN-beta, IFNB, Ifnb1

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 92 % as determined by SDS-PAGE

Bioactivity

Measured in antiviral assay using L929 cells infected with vesicular stomatitisvirus (VSV) . The ED50 for this effect is typically 10-50 pg/mL.

Function

Met1-Asn182

Molecular Weight

The secreted recombinant mouse IFNB1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 402 amino acids and has a calculated molecular mass of 46.7 kDa. As a result of glycosylation, the apparent molecular mass of rmIFNB1/Fc monomer is approximately 58 kDa in SDS-PAGE under reducing conditions.