IFNA7 Protein (N-human IgG1-Fc, Human)

Product Specifications

Abbreviation

IFNA7

Synonyms

IFN-alphaJ, IFNA-J

Host

HEK 293

Tag

N-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 85 % as determined by SDS-PAGE

Bioactivity

Measured in antiviral assays using WISH human amnion cells infected with vesicular stomatitisvirus (VSV) . The ED50 for this effect is 0.1-1 ng/mL.

Function

Cys24-Asp189

Molecular Weight

The recombinant human IFNA7/Fc chimera is a disulfide-linked homodimer. The reduced monomer comprises 427 amino acids with a predicted molecular mass of 48 kDa. rh IFNA7/Fc monomer migrates as an approximately 50 kDa band in SDS-PAGE under reducing conditions.