IFNA5 Protein (N-human IgG1-Fc, Human)

Product Specifications

Abbreviation

IFNA5

Synonyms

IFN-alpha-5, IFN-alphaG, INA5, INFA5, leIF G

Host

HEK 293

Tag

N-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Measured in antiviral assays using WISH human amnion cells infected with vesicular stomatitis virus (VSV) . The EC50 for this effect is 0.16-0.8 ng/mL.

Function

Leu22-Glu189

Molecular Weight

The recombinant human IFNα G/Fc chimera is a disulfide-linked homodimer. The reduced monomer comprises 405 amino acids with a predicted molecular mass of 46.3 kDa. As a result of glycosylation, rh IFNα G/Fc monomer migrates as an approximately 48-50 kDa band in SDS-PAGE under reducing conditions.