IFNA2 Protein (N-human IgG1-Fc, Mouse)

Product Specifications

Abbreviation

IFNA2

Synonyms

If1ai7, Ifa2, Ifna2

Host

HEK 293

Tag

N-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 88 % as determined by SDS-PAGE

Bioactivity

1. Measured in antiviral assays using L929 cells infected with vesicular stomatitisvirus (VSV) . The ED50 for this effect is 1-8 ng/mL. 2. Immobilized Mouse IFNAR1 His (Cat:50469-M08H) at 2 μg/mL (100 μL/well) can bind Mouse Interferon alpha 2/IFNA2 hFc (Cat:50525-M01H), the EC50 of Mouse Interferon alpha 2/IFNA2 hFc (Cat:50525-M01H) is 10-80 ng/mL.

Function

Cys24-Glu190

Molecular Weight

The recombinant mouse IFNA2/Fc is a disulfide-linked homodimer. The reduced monomer comprises 427 amino acids and has a calculated molecular mass of 47.8 kDa. The apparent molecular mass of the monomer is approximately 52 kDa in SDS-PAGE under reducing conditions.