ICOSLG Protein (C-human IgG1-Fc, Human)
Product Specifications
Abbreviation
ICOSLG
Synonyms
B7-H2, B7h, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, IMD119, KIAA0653, LICOS
Host
HEK 293
Tag
C-human IgG1-Fc
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 95 % as determined by SDS-PAGE. ≥ 85 % as determined by SEC-HPLC.
Bioactivity
1.Immobilized Recombinant Human ICOS Ligand / B7-H2 / ICOSLG Protein (Fc Tag) (Cat:11559-H02H) at 2 μg/ml (100 μl/well) can bind Recombinant Human ICOS / AILIM / CD278 Protein (His & Fc Tag) (Cat:10344-H03H), The EC50 is 8-30 ng/mL (QC tested) . 2.Immobilized Recombinant Human ICOS Protein (His Tag) (Cat: 10344-H08H1) at 5 μg/mL (100 μL/well) can bind Recombinant Human ICOS Ligand / B7-H2 / ICOSLG Protein (Fc Tag) (Cat: 11559-H02H), the EC50 is 7.2 ng/mL (Routinely tested) .
Function
Met1-Ser258
Molecular Weight
The recombinant human ICOSLG/Fc is a disulfide-linked homodimer. The reduced monomer comprises 481 amino acids and has a predicted molecular mass of 53.7 kDa. The apparent molecular mass of the protein is approximately 66-76 and 33 kDa in SDS-PAGE under reducing conditions.
Species
Human
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