ICOSLG Protein (C-human IgG1-Fc & His, Mouse)

Product Specifications

Abbreviation

ICOSLG

Synonyms

B7h2, B7rp1, Icosl, Icoslg

Host

HEK 293

Tag

C-human IgG1-Fc & His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Immobilized Recombinant Mouse ICOS / AILIM / CD278 Protein (Fc Tag) (Cat:50466-M02H) at 2 μg/ml (100 μl/well) can bind Recombinant Mouse ICOS Ligand / B7-H2 / ICOSLG Protein (His & Fc Tag) (Cat:50190-M03H), The EC50 is 25-80 ng/mL.

Function

Met1-Lys279

Molecular Weight

The secreted recombinant mouse B7-H2/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer comprises 481 amino acids with a predicted molecular mass of 54.3 kDa. As a result of glycosylation, it migrates as an approximately 75-85 kDa band in SDS-PAGE under reducing conditions.