ICOS Protein (C-human IgG1-Fc & His, Human)

Product Specifications

Abbreviation

ICOS

Synonyms

AILIM, CD278, CVID1

Host

HEK 293

Tag

C-human IgG1-Fc & His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

Immobilized Recombinant Human ICOS Ligand / B7-H2 / ICOSLG Protein (Fc Tag) (Cat:11559-H02H) at 2 μg/ml (100 μl/well) can bind Recombinant Human ICOS / AILIM / CD278 Protein (His & Fc Tag) (Cat:10344-H03H), The EC50 is 8-30 ng/mL.

Function

Met1-Phe141

Molecular Weight

The recombinant human ICOS/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 368 amino acids and predicts a molecular mass of 41.6 kDa. The apparent molecular mass of rhICOS/Fc monomer is approximately 50 kDa due to glycosylation.