ICAM1 Protein (C-His, Mouse)

Product Specifications

Abbreviation

ICAM1

Synonyms

CD54, Icam-1, Icam1, Ly-47, MALA-2

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 96 % as determined by SDS-PAGE ≥ 95 % as determined by SEC-HPLC.

Bioactivity

Measured by the ability of the immobilized protein to support the adhesion of PMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemia cells. When cells are added to mouse ICAM1 coated plates (12.5 μg/mL, 100 μL/well), approximately > 40% cells will adhere specifically.

Function

Met1-Asn485

Molecular Weight

The recombinant mouse ICAM1 consists of 469 amino acids after removal of the signal peptide. and has a predicted molecular mass of 51.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm ICAM1 is approximately 80-90 kDa due to glycosylation.