HMGB1 Protein (N-human IgG1-Fc, Mouse)

Product Specifications

Abbreviation

HMGB1

Synonyms

HMG-1, Hmg1, Hmgb1, p30, SBP-1

Host

HEK 293

Tag

N-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 85 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

Measured by its ability to bind mouse AGER-His in functional ELISA.

Function

Met1-Glu215

Molecular Weight

The recombinant mouse HMGB1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 475 amino acids and has a calculated molecular mass of 53.3 kDa. The apparent molecular mass of the monomer is approximately 57 kDa in SDS-PAGE under reducing conditions.