GHR Protein (C-His, Mouse)

Product Specifications

Abbreviation

GHR

Synonyms

GHBP, Ghr, GHR/BP

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

Measured by its ability to Inhibit activation of GH pathway in a Luciferase receptor Assay System.The ED50 for this effect is typically 0.1-1μg/mL in the presence of 50 ng/mL human growth hormone.

Function

Met1-Gln273

Molecular Weight

The recombinant mouse GHR consists of 260 amino acids and has a predicted molecular mass of 30.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmGHR is approximately 40-45 kDa due to glycosylation.