GHR Protein (C-human IgG1-Fc, Rat)

Product Specifications

Abbreviation

GHR

Synonyms

Ghr, GHR/BP

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to Inhibit activation of GH pathway in a Luciferase receptor Assay System.The ED50 for this effect is typically 0.03-0.3 μg/mL in the presence of 50 ng/mL human growth hormone.

Function

Met1-Arg265

Molecular Weight

The recombinant rat GHR/Fc is a disulfide-linked homodimer. The reduced monomer comprises 488 amino acids and has a predicted molecular mass of 55.4 kDa. The apparent molecular mass of the protein is approximately 66 kDa in SDS-PAGE under reducing conditions.