GFRAL Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

GFRAL

Synonyms

BA360D14.1, C6orf144, GRAL, UNQ9356, UNQ9356/PRO34128

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

Immobilized Recombinant Human GDF-15 / GDF15 Protein (His Tag) (Mature Form) (Cat: 10936-H07Y) at 2 μg/mL (100 μL/well) can bind Recombinant Human GFRAL Protein (Fc Tag) (Cat: 27245-H02H), the EC50 is 7.0-21.0 ng/mL.

Function

Ser19-Glu351

Molecular Weight

The recombinant Human GFRAL consisting of 571 amino acids and has a calculated molecular mass of 64.53 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 69.3 kDa protein in SDS-PAGE under reducing conditions.