GFRA1 Protein (C-His, Mouse)

Product Specifications

Abbreviation

GFRA1

Synonyms

Gdnfra, Gfra1, GFRalpha-1, Trnr1

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 98 % as determined by SDS-PAGE

Bioactivity

1. Measured in a cell proliferation assay using SH‐SY5Y human neuroblastoma cells. The ED50 for this effect is typically 0.4-2 μg/mL in the presence of 40 ng/mL Recombinant Human GDNF. 2. Measured by its ability to bind with human GDNF (Cat:10561-HNCH) in a functional ELISA.

Function

Met1-Ser425

Molecular Weight

The secreted recombinant mouse GFRα1consists of 412 amino acids and has a calculated molecular mass of 46.3 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 55-60 kDa protein in SDS-PAGE under reducing conditions.