GFRA1 Protein (C-His, Human)

Product Specifications

Abbreviation

GFRA1

Synonyms

GDNFR, GDNFR-alpha-1, GDNFRA, GFR-ALPHA-1, GFRalpha-1, RET1L, RETL1, RHDA4, TRNR1

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 98 % as determined by SDS-PAGE. ≥ 85 % as determined by SEC-HPLC.

Bioactivity

Immobilized Recombinant Human GDNF Protein (Cat:10561-HNCH) at 2 μg/mL (100 μL/well) can bind Recombinant Human GFRA1 / GFRα1 / GDNFRA Protein (His Tag) (Cat:10330-H08H), the EC50 is 15-48 ng/mL.

Function

Met1-Ser424

Molecular Weight

The recombinant human GFRα1 consists of 411 amino acids after removal of the signal peptide and predicts a molecular mass of 46 kDa. As a result of glycosylation, the rhGFRα1 migrates as an approximately 55-60 kDa protein in SDS-PAGE under reducing conditions.