GFRA1 Protein (C-human IgG1-Fc, Rat)

Product Specifications

Abbreviation

GFRA1

Synonyms

Gdnfra, Gfra1, Retl1, Trnr1

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Immobilized rat His-GDNF (78-211) (Cat:80050-R07B) at 10 μg/ml (100 μl/well) can bind rat GFRA1-Fc, The EC50 of rat GFRA1-Fc is 20-46.6 ng/ml.

Function

Met1-Leu445

Molecular Weight

The recombinant rat GFRA1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 662 amino acids and has a predicted molecular mass of 73.8 kDa. The apparent molecular mass of the protein is approximately 85 kDa in SDS-PAGE under reducing conditions.