GFRA1 Protein (C-human IgG1-Fc, Rat)
Product Specifications
Abbreviation
GFRA1
Synonyms
Gdnfra, Gfra1, Retl1, Trnr1
Host
HEK 293
Tag
C-human IgG1-Fc
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 90 % as determined by SDS-PAGE
Bioactivity
Immobilized rat His-GDNF (78-211) (Cat:80050-R07B) at 10 μg/ml (100 μl/well) can bind rat GFRA1-Fc, The EC50 of rat GFRA1-Fc is 20-46.6 ng/ml.
Function
Met1-Leu445
Molecular Weight
The recombinant rat GFRA1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 662 amino acids and has a predicted molecular mass of 73.8 kDa. The apparent molecular mass of the protein is approximately 85 kDa in SDS-PAGE under reducing conditions.
Species
Rat
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