GCGR Protein (N-Flag-Strep & C-His, Human)

Product Specifications

Abbreviation

GCGR

Synonyms

GGR, GL-R, MVAH

Host

HEK 293

Tag

N-Flag-Strep & C-His

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 90 % as determined by SDS-PAGE.

Bioactivity

1. Immobilized Recombinant Human GCGR Protein (Nanodisc, Flag-Strep & His Tag) (Cat: 30122-H91H-NA) at 5 μg/mL (100 μL/well) can bind Crotedumab Derived Anti-GCGR Antibody, Human IgG4, the EC50 is 15-55 ng/mL. 2. Immobilized Recombinant Human GCGR Protein (Nanodisc, Flag-Strep & His Tag) (Cat: 30122-H91H-NA) at 5 μg/mL (100 μL/well) can bind Volagidemab Derived Anti-GCGR Antibody, Human IgG2, the EC50 is 3-15 ng/mL (QC tested) .

Function

Ala26-Asn432

Molecular Weight

The recombinant Human GCGR comprises 440 amino acids and has a predicted molecular mass of 50.67 kDa. It migrates as approximately 54.9 kDa band in SDS-PAGE under reducing conditions.