FOLR1 Protein (C-human IgG1-Fc & AVI, Human)

Product Specifications

Abbreviation

FOLR1

Synonyms

FBP, FOLR, FRalpha, FRα, NCFTD

Host

HEK 293

Tag

C-human IgG1-Fc & AVI

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

1.Immobilized Folic acid-BSA conjugate at 5 μg/mL (100 μL/well) can bind Recombinant Human FOLR1 Protein (ECD, Fc & AVI Tag), Biotinylated (Cat: 11241-H41H-B), the EC50 is 29.5-88.3 ng/mL (QC tested) . 2.Immobilized Recombinant Human FOLR1 Protein (ECD, Fc & AVI Tag), Biotinylated (Cat: 11241-H41H-B) at 1 μg/mL (100 μl/well) on streptavidin precoated (5 μg/mL, 100 μL/well) can bind Anti-FOLR1 (Research grade Luvelta*mab biosimilar), the EC50 is 3.0-9.5 ng/mL (QC tested) . 3.Immobilized Anti-FOLR1 (Research grade Luvelta*mab biosimilar) at 1 μg/mL (100 μL/well) can bind Recombinant Human FOLR1 Protein (ECD, Fc & AVI Tag), Biotinylated (Cat: 11241-H41H-B), the EC50 is 3-10 ng/mL (Routinely tested) .

Function

Met1-Met233

Molecular Weight

The recombinant Human FOLR1 consists of 462 amino acids and predicts a molecular mass of 53.11 kDa. It migrates as an approximately 61.6 kDa band in SDS-PAGE under reducing conditions.

Species

Human