FLT1 Protein (C-His, Rat)

Product Specifications

Abbreviation

FLT1

Synonyms

FLT-1, Flt1, VEGFR-1, Vegfr1

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to inhibit VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC) . The ED50 for this effect is typically 15-70ng/mL in the presence of 10 ng/mL rmVEGF164.

Function

Met1-Glu758

Molecular Weight

The recombinant rat FLT1 comprises 747 amino acids and predicts a molecular mass of 84 kDa. The apparent molecular mass of the recombinant protein is approximately 108-114 kDa in SDS-PAGE under reducing conditions due to glycosylation.