FGFR4 Protein (C-human IgG1-Fc & His, Mouse)

Product Specifications

Abbreviation

FGFR4

Synonyms

Fgfr-4, Fgfr4, Mpk-11

Host

HEK 293

Tag

C-human IgG1-Fc & His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to inhibit FGF acidic (aFGF / FGF1) dependent proliferation of Balb/c3T3 mouse embryonic fibroblasts .The ED50 for this effect is typically 0.1-0.6 μg/mL.

Function

Met1-Asp366

Molecular Weight

The recombinant mouse FGFR4/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 598 amino acids and has a predicted molecular mass of 67 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm FGFR4/Fc monomer is approximately 100-110 kDa due to glycosylation.