FGFR3 Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

FGFR3

Synonyms

ACH, CD333, CEK2, HSFGFR3EX, JTK4

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

> 95 % as determined by SDS-PAGE.

Bioactivity

1.Measured by its ability to inhibit FGF-acidic dependent proliferation of Balb/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 20-120 ng/mL (QC tested) . 2.Recombinant Human FGFR3 / CD333 Protein (alpha (IIIb), Fc Tag) (Cat: 16486-H02H) immobilized on CM5 chip, can bind Recombinant Human aFGF / FGF1 Protein (Cat: 10013-HNAE) with an affinity constant of 1.420 μM as determined in an SPR assay (Biacore 8K) (Routinely tested) .