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FGFR2 Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

FGFR2

Synonyms

BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, KSAM, TK14, TK25

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

1. Measured by its ability to inhibit FGF-acidic dependent proliferation of Balb/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.5-4 ng/mL. 2. Measured by its ability to bind recombinant Fc-FGF10 in a functional ELISA.

Function

Met1-Glu378

Molecular Weight

The recombinant human FGFR2 (alpha (IIIb) ) consists 595 amino acids and predicts a molecular mass of 66.3 kDa.

Species

Human

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