FGFR1 Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

FGFR1

Synonyms

BFGF-R-1, BFGFR, CD331, CEK, ECCL, FGFBR, FGFR-1, FLG, FLT-2, FLT2, H2, H3, H4, H5, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

<1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 85 % as determined by SEC-HPLC.

Bioactivity

Measured by its ability to inhibit FGF-acidic dependent proliferation of Balb/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.1-0.6 ng/mL

Function

Met1-Lys310

Molecular Weight

The recombinant human FGFR1 alpha (IIIb) consists of 590 amino acids and predicts a molecular mass of 65.7 kDa. As a result of glycosylation, it migrates as an approximately 113.3 kDa band in SDS-PAGE under reducing conditions.