FCGRT & B2M Protein (C-AVI & His, Cynomolgus)
Product Specifications
Abbreviation
FCGRT & B2M
Host
HEK 293
Tag
C-AVI & His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 95 % as determined by SDS-PAGE, ≥ 90 % as determined by SEC-HPLC, ≥ 90% as determined by SEC-MALS (Routinely tested) .
Bioactivity
1.Immobilized Anti-CD20 Antibody at 2 μg/ml (100 μl/well) can bind Recombinant Cynomolgus FCGRT&B2M Heterodimer Protein (His&AVI Tag), Biotinylated (Cat: CT084-C27H-B), the EC50 is 80-240 ng/mL. 2.Loaded Biotinylated Cynomolgus FcRn recombinant protein (His & Avi Tag) (Cat. CT084-C27H-B) on SA Biosensor, can bind IgG1 Fc (Cat. 10702-HNAC) with an affinity constant of 0.08 μM as determined in a BLI assay (Sartorius Octet Red384) .
Function
Met 1-Ser 297 & Met 1-Met 119
Molecular Weight
The recombinant cynomolgus FCGRT&B2M consists of 399 (300+99) amino acids and predicts a molecular mass of 45.3 (33.7+ 11.6) KDa. The molecular weight of this protein is around 46-56 kDa verified by SEC-MALS (Routinely tested) .
Species
Cynomolgus
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